Dynamic Light Scattering Detectors

In a dynamic light scattering (DLS) measurement, the time-dependent fluctuations in the scattered light are measured by a fast photon counter. The fluctuations are directly related to the rate of diffusion of the molecule through the solvent. Therefore, the fluctuations can be analyzed to determine a hydrodynamic radius for the sample.


DynaPro NanoStar™:

  • Batch Dynamic (DLS) and Static Light Scattering (SLS)
  • Size Range (Radius): 0,2 nm to 2500 nm
  • Minimum Concentration: 0,1 mg/ml Lysozyme
  • Minimum sample volume: 1.25 µl (standard quartz-cuvette). Disposable cuvettes available: 4 µl and 50 µl
  • Temperature control: -15°C to 150°C
  • Automated attenuation of laser and detector
  • Molar mass range: 300 Da to 106 Da
  • Combination of DLS and SLS can distinguish between aggregation and conformation change in sample
  • Instrument can also be used online for chromatography work (together with SEC-MALS)
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  • Most versatile Quasi Elastic Light Scattering (QELS) device for online particles sizes and distributions
  • Embedded in Multi-Angle Light Scattering detector
  • Multiple Tau correlation design with a fixed range of channel from 480 nsec to ~1 hour (real-time).
  • No sample time optimization required
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DynaPro™ Plate Reader:

  • High-throughput, automated Dynamic Light Scattering
  • 96, 384, 1536 industry-standard well plate formats (no special plates needed)
  • Size range: 1 nm to 1000 nm
  • Minimum concentration 0,125 mg/mL Lysozyme
  • Temperature control: 4° to 85°C
  • Average read time per well of 5-20 sec
  • Minimum sample volumes: 4 µl per well (1536 well plate)
  • Screen large number of samples automatically
  • Fast measurements, including temperature scans of multiple samples
  • Easy measurement of replicates of the same sample
  • Ideally suited for multi-user facility and when other screening techniques already use microwell plates
  • Eliminate cross-contamination
  • No need of washing/changing of cuvettes
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  • Massive-Parallel Phase Analysis Light Scattering (MP-PALS)
  • Dynamic Light Scattering (DLS) optional
  • Allows zeta potential, mobility, stability and sizes measurements of nanoparticles and fragile biomolecules down to only 1 nm!
  • Measures faster and uses less voltage than conventionel zeta potential analyzers
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For more information about dynamic light scattering theory, please view our theory section.

Do you want more information? We would be delighted to hear from you!