GPC/SEC Detection Systems



Size Exclusion Chromatography (SEC) also known as Gel Permeation Chromatography (GPC) has been widely used to characterize the molar mass and aggregation state of proteins as well as the molar mass distribution of biopolymers and polymers in solution. Wyatt Technology offers you a complete range of GPC/SEC systems available for GPC/SEC separation followed by absolute macromolecular characterization.






Hardware Components:


ASTRA® 6 Software - Comprehensive Macromolecular Analysis. Simplified.





Wyatt GPC/SEC systems come with ASTRA® 6 - the most comprehensive and user-friendly macromolecular characterization software package available today. Complete with networked data collection, revolutionary analysis capabilities, and 21 CFR Part 11 compliance, ASTRA® can take your research to new levels including:

  • Molar mass via Conventional and Universal Column Calibration
  • Molecular Conformation
  • Absorbance correction
  • Band broadening correction
  • Molar mass via light scattering
  • Zimm Plot/ Second virial coefficient (A2)
  • Particles and number density
  • Online DLS
  • DLS batch Regularization and Cumulants
  • Protein conjugates and co-polymers
  • dn/dc and UV extinction determination
  • Viscometry
  • Intrinsic Viscosity Models
  • Branching calculations
  • Distributions
  • Error analysis


We would be delighted to hear from you!

Please contact us if you are looking for a complete GPC/SEC system or would like to add a detector to your existing system.






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