Product Overview




 Field Flow Fractionation (FFF)  
Eclipse™ AF4 Eclipse™ DUALTEC

Asymmetric Flow-FFF (AF4) for high-resolution separation and fractionation of proteins, nanoparticles, polymers, etc.

Hollow-Fiber Flow-FFF (HF5) and Asymmetric Flow-FFF (AF4) - combined in one system - for high-resolution separation and fractionation of proteins, nanoparticles, polymers, etc.

 Multi-Angle Light Scattering (MALS)
DAWN® HELEOS™ II miniDAWN™ TREOS

18 angle MALS light scattering instrument for absolute molecular weight, size, & conformation of macromolecules in solution.

3 angle MALS light scattering instrument for absolute molecular weight, size, & conformation of macromolecules in solution.

 Dynamic Light Scattering (DLS or QELS)
DynaPro™ NanoStar WyattQELS™ DynaPro™ Plate Reader

Stand alone Dynamic Light Scattering instrument for measuring the sizes of proteins, nanoparticles, vesicles, and more!

Quasi-elastic light scattering (QELS or DLS) which interfaces to the MALS instruments for on-line size measurements of proteins, nanoparticles, etc.

Automated high throughput dynamic light scattering technology to measure the sizes of proteins, nanoparticles, etc. in 96 or 384 or 1536 well plates.

 Refractive Index (RI)  Viscometer (VI)
Optilab® T-rEX ViscoStar™ II

Refractive index detector to measure the concentration of an analyte in solution, the dn/dc, and the absolute refractive index of the solution

On-line differential viscometer to measure the intrinsic viscosity and Mark Houwink-Sakurada (MHS) parameters of polymers.

 Electrophoretic Mobility  Automated Composition Gradients
Möbiuζ™ Calypso

Electrophoretic Mobility detector to measure not only large particles, but also to measure protein samples including antibody formulations, bovine serum albumin and lysozyme, all down to 1 nm!

Macromolecular interactions such as protein-protein association, aggregation, and kinetics may be characterized via Composition-Gradient MALS. Calypso automates sample preparation, delivery to detectors, data acquisition and analysis for measuring equilibrium association constants of reversible self- and hetero-associations, reaction rates, virial coefficients and dn/dc.



Wyatt Technology is the world leader in providing the most advanced macromolecular and nanoparticle characterization tools. These instruments and software may be used to determine the absolute molecular weight and or size of macromolecules and nanoparticles and include: multi-angle light scattering, dynamic light scattering, high through-put dynamic light scattering, field flow fractionation, refractive index and viscometry detection.